Early effects of gliadin on enterocyte intracellular signalling involved in intestinal barrier function

"Despite the progress made in understanding the immunological aspects of the pathogenesis of coeliac disease (CD), the early steps that allow gliadin to cross the intestinal barrier are still largely unknown. The aim of this study was to establish whether gliadin activates a zonulin dependent enterocyte intracellular signalling pathway(s) leading to increased intestinal permeability."

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Endogenous retroviruses and the placenta

Heidmann believes that without endogenous retroviruses mammals might never have developed a placenta, which protects the fetus and gives it time to mature, which eventually led to live birth, one of the hallmarks of human evolutionary success over birds, reptiles, and fish. Eggs cannot eliminate waste or draw the maternal nutrients required to develop the large brains that have made mammals so versatile. “These viruses made those changes possible. It is quite possible that, without them, human beings would still be laying eggs.”

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One man's meat is another man's poison

Cf. [Lucretius De Rerum Natura iv. 637] quod ali cibus est aliis fuat acre venenum, what is food to one person may be bitter poison to others.

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Meat may be the reason humans outlive apes

"Genetic changes that apparently allow humans to live longer than any other primate may be rooted in a more carnivorous diet."

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The Vegetarian Myth

"The truth is that agriculture is the most destructive thing humans have done to the planet, and more of the same won’t save us. The truth is that agriculture requires the wholesale destruction of entire ecosystems. The truth is also that life isn’t possible without death, that no matter what you eat, someone has to die to feed you."

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